Bone Marrow Concentrate

Bone Marrow Concentrate

As a leader in cutting-edge orthopedic treatments, Paul Eliot Hughes, MD, has over a decade of experience in regenerative medicine, bone marrow concentrate and platelet rich plasma. At his San Mateo and Sacramento orthopedic practice, Dr. Hughes offers cellular therapy as an alternative to surgery when you need relief from chronic joint or tissue pain. He can recommend regenerative medicine as an effective treatment for sports-related injuries, degenerative disease damage, or to slow down the progress of age-related conditions that cause pain and limited mobility.

Bone Marrow Concentrate: Bone marrow concentrate (BMC) treatments collect platelets and cells from bone marrow tissue. Mesenchymal cells (MSCs) and other adult cells are components of BMC. Once the adult cell-containing BMC is prepared, Dr. Hughes injects it into the injured area of the joint. The platelets can release growth factors that encourage new tissue to form. The mesenchymal stem cells can control inflammation and help damaged cells recover. MSCs can also differentiate into cartilage, bone, and/or other connective tissues.

Find out if regenerative medicine is right for you by calling the office or requesting an appointment.


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What is regenerative medicine?

Adult autologous mesenchymal cells are supported by a special ability to help facilitate repair or replace other cells and tissues in your body that become damaged by disease or traumatic injury. These cells develop into other specific cells, including:


  • Bone
  • Muscle
  • Tendon
  • Cartilage


Using regenerative medicine, Dr. Hughes can help alleviate your chronic pain and increase your mobility in the injured area without the need for surgery.

Where do mesenchymal cells come from?

One of the benefits of regenerative medicine is that, in many cases, Dr. Hughes can extract these important cells directly from your own body. Typically, he can harvest cells from your bone marrow. Marrow is preferred because it has the highest concentration of cells available.

How does treatment work?

Once Dr. Hughes extracts the bone marrow aspirate, he uses a high-quality centrifuge to separate the cells from the rest of the substances in the marrow. This creates a high concentration of cells ready for injection into the treatment area. Dr. Hughes uses local not general anesthetic, numbing the area of injection to ensure your outpatient treatment is pain-free and comfortable. After the injections, you can go home to rest before returning to your usual activities.


 You should experience a significant reduction in painful joints and muscles and begin healing from injuries to your tendons, ligaments, and cartilage.

Am I a good candidate for regenerative medicine?

Depending on the nature of your injury or disease, Dr. Hughes could recommend  regenerative medicine technique to alleviate pain and enhance mobility.



To ensure you’re a good candidate for this type of treatment, Dr. Hughes evaluates your overall health and medical history. He also discusses your goals in treatment and expectations of pain relief.